Optimal allocation of patients in titration to fixed dose trials

cg.contactsudhir@math.niu.eduen_US
cg.contributor.centerInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.contributor.centerNorthern Illinois Universityen_US
cg.contributor.centerGovernment of Uttar Pradesh, Department of Fisheriesen_US
cg.contributor.funderInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.contributor.projectCommunication and Documentation Information Services (CODIS)en_US
cg.contributor.project-lead-instituteInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.creator.idSingh, Murari: 0000-0001-5450-0949en_US
cg.date.embargo-end-dateTimelessen_US
cg.identifier.doihttps://dx.doi.org/10.1016/S0378-3758(02)00214-8en_US
cg.isijournalISI Journalen_US
cg.issn0378-3758en_US
cg.issue1-2en_US
cg.journalJournal of Statistical Planning and Inferenceen_US
cg.volume106en_US
dc.contributorHosmane, Balakrishnaen_US
dc.contributorSingh, Murarien_US
dc.contributorSingh, Rajendraen_US
dc.creatorGupta, Sudhiren_US
dc.date.accessioned2021-07-29T00:03:40Z
dc.date.available2021-07-29T00:03:40Z
dc.description.abstractOptimal allocations of patients to different arms of a fixed dose titration trial for estimating the dose–response relationship are provided. Optimal sample sizes are derived for the case where the linearizing transformation is log(dose). Optimal sample sizes for predicting the response are also derived. For equi-spaced dose levels on the log scale, the determination of optimal doses is also considered.en_US
dc.identifierhttps://mel.cgiar.org/dspace/limiteden_US
dc.identifier.citationSudhir Gupta, Balakrishna Hosmane, Murari Singh, Rajendra Singh. (1/8/2002). Optimal allocation of patients in titration to fixed dose trials. Journal of Statistical Planning and Inference, 106 (1-2), pp. 215-223.en_US
dc.identifier.statusTimeless limited accessen_US
dc.identifier.urihttps://hdl.handle.net/20.500.11766/13536
dc.languageenen_US
dc.publisherElsevier (12 months)en_US
dc.sourceJournal of Statistical Planning and Inference;106,(2002) Pagination 215-223en_US
dc.subjectclinical trialen_US
dc.subjectdose-escalation designen_US
dc.subjectoptimal allocationen_US
dc.subjectlog(dose) transformationen_US
dc.subjecttitration trialen_US
dc.titleOptimal allocation of patients in titration to fixed dose trialsen_US
dc.typeJournal Articleen_US
dcterms.available2002-06-03en_US
dcterms.extent215-223en_US
dcterms.issued2002-08-01en_US
mel.impact-factor1.111en_US

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